Recombinant TSH receptor 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant TSH receptor 抗体 (ABIN7882481)
抗原
See all TSH receptor (TSHR) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
原理
- Recombinant TSH Receptor Antibody / B-Chain (azide and preservative free)
-
纯化方法
- Protein A/G affinity
-
免疫原
- Recombinant human TSHR B-Chain protein was used as the immunogen for the recombinant TSH Receptor antibody.
-
亚型
- IgG, kappa
-
-
-
-
应用备注
- Optimal dilution of the recombinant TSH Receptor antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- -20 °C
-
储存方法
- Aliquot the recombinant TSH Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
-
别名
- TSH Receptor
-
背景
- Thyroid-stimulating hormone (TSH, also known as thyrotropin) is a glycoprotein involved in the control of thyroid structure and metabolism, which stimulates the release of the thyroid hormones. TSH is regulated by thyroid hormone (T3) and various retinoid compounds. TSH binds to the thyroid-stimulating hormone receptor (TSHR), which is cleaved into two subunits, A and B, and plays a major role in regulating thyroid function. The third cytoplasmic loop of TSHR has been identified as critical for its role in regulating inositol phosphate and cAMP formation. In Grave s disease, an autoimmune disorder, TSHR is activated by autoantibodies, which may be stimulated by the cleavage of the A and B subunits.
-
UniProt
- P16473
-
途径
- Thyroid Hormone Synthesis
抗原
-