Thyroglobulin 抗体
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北京 101111
Quick Overview for Thyroglobulin 抗体 (ABIN7882471)
抗原
See all Thyroglobulin (TG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Thyroglobulin Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- Human thyroid follicular cells were used as the immunogen for this anti-Thyroglobulin antibody.
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亚型
- IgG1, kappa
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anti-Thyroglobulin (TG) (AA 2659-2768) antibody
TG 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-Thyroglobulin (TG) antibodyTG 适用: 人, 小鼠, 大鼠 IHC 宿主: 小鼠 Monoclonal r2H11 unconjugated Recombinant Antibody
anti-Thyroglobulin (TG) antibodyTG 适用: 人 IHC 宿主: 小鼠 Monoclonal r6E1 unconjugated Recombinant Antibody
anti-Thyroglobulin (TG) antibodyTG 适用: 人 IHC 宿主: 兔 Monoclonal 189R unconjugated Recombinant Antibody
anti-Thyroglobulin (TG) (AA 2083-2333) antibodyTG 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thyroglobulin (TG) antibodyTG 适用: 人, Cow IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Thyroglobulin (TG) antibodyTG 适用: 人 IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Thyroglobulin (TG) antibodyTG 适用: 人 IHC 宿主: 兔 Monoclonal TGB-1970R unconjugated Recombinant Antibody
anti-Thyroglobulin (TG) antibodyTG 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thyroglobulin (TG) (C-Term) antibodyTG 适用: 人 IHC (p) 宿主: 兔 Monoclonal E23-Y unconjugated
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应用备注
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The optimal dilution of the anti-Thyroglobulin antibody for each application should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the anti-Thyroglobulin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Thyroglobulin (TG)
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别名
- Thyroglobulin
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背景
- Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.
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UniProt
- P01266
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途径
- Thyroid Hormone Synthesis
抗原
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