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TYMS 抗体

The 兔 单克隆 anti-TYMS antibody (Clone ADAA-20) (ABIN7882469) specifically detects TYMS in WB. The antibody is reactive with 人, 小鼠, 大鼠 和 猴 samples.
产品编号 ABIN7882469
发货至: 中国
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Quick Overview for TYMS 抗体 (ABIN7882469)

抗原

See all TYMS 抗体
TYMS (Thymidylate Synthetase (TYMS))

适用

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人, 小鼠, 大鼠, 猴

宿主

  • 72
  • 71
  • 1

克隆类型

  • 97
  • 47
单克隆

标记

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This TYMS antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

ADAA-20
  • 原理

    Thymidylate Synthase Antibody

    纯化方法

    Affinity purified

    免疫原

    A synthetic peptide specific to human Thymidylate Synthase / TYMS was used as the immunogen for the Thymidylate Synthase antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Thymidylate Synthase antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the Thymidylate Synthase antibody at -20oC.
  • 抗原

    TYMS (Thymidylate Synthetase (TYMS))

    别名

    Thymidylate Synthase

    背景

    Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occurring antisense transcript, mitochondrial enolase superfamily member 1, vary inversely when cell-growth progresses from late-log to plateau phase. Polymorphisms in this gene may be associated with etiology of neoplasia, including breast cancer, and response to chemotherapy. [RefSeq]

    UniProt

    P04818

    途径

    Mitotic G1-G1/S Phases
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