Recombinant SNCA 抗体
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北京 101111
Quick Overview for Recombinant SNCA 抗体 (ABIN7882417)
抗原
See all SNCA 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Alpha-Synuclein Antibody / SNCA
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纯化方法
- Affinity chromatography
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免疫原
- A peptide sequence specific to Alpha-Synuclein was used as the immunogen for the Alpha-Synuclein antibody.
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亚型
- IgG
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anti-Synuclein, alpha (SNCA) (pSer129) antibody
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (FITC)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal FITC
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (Biotin)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (HRP)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal HRP
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (PE)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal PE
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (PerCP)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal PerCP
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (Atto 488)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 488
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (Atto 390)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 390
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (APC)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal APC
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibodySNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Alpha-Synuclein antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Alpha-Synuclein antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SNCA (Synuclein, alpha (SNCA))
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别名
- Alpha-Synuclein
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背景
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Alpha-Synuclein (SCNA) is a small, soluble protein predominantly expressed in the brain, particularly in presynaptic nerve terminals. It plays a role in synaptic vesicle trafficking, neurotransmitter release regulation, and neuronal plasticity. Alpha-Synuclein can adopt different conformations, with certain aggregated forms being implicated in neurodegenerative processes.
Mutations or abnormal accumulation of Alpha-Synuclein are strongly linked to synucleinopathies, including Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. Its aggregation into insoluble fibrils is a key pathological hallmark of these conditions. Studying Alpha-Synuclein expression and distribution provides valuable insights into neuronal function, protein misfolding, and neurodegenerative disease mechanisms.
Using a high-quality Alpha-Synuclein antibody enables sensitive detection in assays such as western blot, immunohistochemistry, and ELISA. An Alpha-Synuclein antibody from NSJ Bioreagents offers reliable performance for researchers investigating protein aggregation, neurodegenerative disease progression, and potential therapeutic interventions. Selecting the appropriate Alpha-Synuclein antibody is essential for generating reproducible and accurate results in both basic and applied neuroscience research.
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UniProt
- P37840
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途径
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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