SYNPO 抗体
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北京 101111
Quick Overview for SYNPO 抗体 (ABIN7882410)
抗原
See all SYNPO 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SYNPO Antibody / Synaptopodin
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序列
- EKPKVTPNPD LLDLVQTADE KRRQRDHGEV GMEEE
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纯化方法
- Affinity purified
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免疫原
- Amino acids EKPKVTPNPDLLDLVQTADEKRRQRDHGEVGMEEE from the human protein were used as the immunogen for the SYNPO antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SYNPO antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SYNPO antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SYNPO (Synaptopodin (SYNPO))
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别名
- SYNPO
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背景
- The spine apparatus (SA) is a specialized form of endoplasmic reticulum (ER) that is found in a subpopulation of dendritic spines in central neurons. The SA consists of a series of stacked discs that are though to be connected to each other and to the dendritic system of ER-tubules. The actin binding protein synaptopodin (which has originally been described in podocytes of the kidney) is an essential component of the SA. Mice that lack the gene for synaptopodin do not form a spine apparatus. The SA is believed to play a critical role in learning and memory. In summary, an important function of the spine apparatus is the regulation of plasticity at individual synapses, a process known as metaplasticity. The International Radiation Hybrid Mapping Consortium mapped the SYNPO gene to chromosome 5.
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UniProt
- Q8N3V7
抗原
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