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Synaptophysin 抗体

The 小鼠 单克隆 anti-Synaptophysin antibody (Clone 3G12) (ABIN7882406) specifically detects Synaptophysin in WB. The antibody is reactive with 大鼠 和 小鼠 samples.
产品编号 ABIN7882406
发货至: 中国
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Quick Overview for Synaptophysin 抗体 (ABIN7882406)

抗原

See all Synaptophysin (SYP) 抗体
Synaptophysin (SYP)

适用

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大鼠, 小鼠

宿主

  • 94
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小鼠

克隆类型

  • 119
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单克隆

标记

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This Synaptophysin antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

3G12
  • 原理

    Synaptophysin Antibody / SYP

    序列

    MLLLADMDVV NQLVAGGQFR VVKEPL

    纯化方法

    Affinity purified

    免疫原

    Amino acids MLLLADMDVVNQLVAGGQFRVVKEPL from the human protein were used as the immunogen for the Synaptophysin antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the Synaptophysin antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Synaptophysin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Synaptophysin (SYP)

    别名

    Synaptophysin

    背景

    SYP (Synaptophysin) is located on the short arm of X chromosome (Xp11.23-p11.22). The protein is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38 kDa. It is present in neuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for neuroendocrine tumors, and its ubiquity at the synapse has led to the use of synaptophysin immunostaining for quantification of synapses. Also, the protein binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR).

    UniProt

    P08247

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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