Recombinant SOX2 抗体
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北京 101111
Quick Overview for Recombinant SOX2 抗体 (ABIN7882358)
抗原
See all SOX2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- SOX2 Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant fragment of human SOX2 protein was used as the immunogen for the SOX2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SOX2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the SOX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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别名
- SOX2
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背景
- SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.
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UniProt
- P48431
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途径
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
抗原
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