Spectrin beta Chain, Erythrocyte (SPTB) 抗体
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Quick Overview for Spectrin beta Chain, Erythrocyte (SPTB) 抗体 (ABIN7882348)
抗原
See all Spectrin beta Chain, Erythrocyte (SPTB) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- SPTB Antibody / Spectrin beta
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纯化方法
- Protein G affinity chromatography
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免疫原
- Red cell membranes were used as the immunogen for this Spectrin beta antibody.
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亚型
- IgG2a, kappa
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anti-Spectrin beta Chain, Erythrocyte (SPTB) antibody
SPTB 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ELISA 宿主: 小鼠 Monoclonal RG-26 unconjugated
anti-Spectrin beta Chain, Erythrocyte (SPTB) (AA 703-2137) antibodySPTB 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Spectrin beta Chain, Erythrocyte (SPTB) antibodySPTB 适用: 人 WB, IHC, IP 宿主: 小鼠 Monoclonal DB2 unconjugated
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应用备注
- Optimal dilution of the SPTB antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the SPTB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Spectrin beta Chain, Erythrocyte (SPTB)
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别名
- SPTB
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背景
- Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming a scaffolding and playing an important role in maintenance of plasma membrane integrity and cytoskeletal structure. In certain types of brain injury such as diffuse axonal injury, spectrin is irreversibly cleaved by the proteolytic enzyme calpain, destroying the cytosketelon. Spectrin cleavage causes the membrane to form blebs and ultimately to be degraded, usually leading to cell death.
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UniProt
- P11277
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途径
- Regulation of Actin Filament Polymerization
抗原
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