Recombinant Somatostatin 抗体
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Quick Overview for Recombinant Somatostatin 抗体 (ABIN7882334)
抗原
See all Somatostatin (SST) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- SST Antibody / Somatostatin
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human Somatostatin 28 was used as the immunogen for the SST antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SST antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the SST antibody at -20oC.
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- Somatostatin (SST)
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别名
- SST
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物质类
- Chemical
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背景
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SST antibody detects somatostatin, a peptide hormone encoded by the SST gene. Somatostatin exists in two biologically active forms, somatostatin 14 and somatostatin 28, generated by alternative processing of a larger precursor. These peptides act as inhibitory hormones and neurotransmitters, regulating secretion of growth hormone, insulin, glucagon, and numerous gastrointestinal peptides. Somatostatin achieves its effects by binding to somatostatin receptors, a family of G protein coupled receptors expressed across many tissues.
SST antibody is widely used in endocrinology, neuroscience, and cancer research. In the pituitary gland, somatostatin regulates growth hormone release. In the pancreas, it modulates insulin and glucagon secretion. In the gastrointestinal tract, it suppresses acid secretion and motility. By detecting somatostatin, researchers can evaluate how this peptide coordinates endocrine and paracrine regulation across multiple organ systems.
Immunohistochemistry maps somatostatin producing cells in pancreatic islets, hypothalamus, and gastrointestinal mucosa. Immunofluorescence reveals somatostatin localization in neurons and endocrine cells, while ELISA enables quantitative analysis in serum or tissue extracts. These techniques make SST antibody a versatile tool for endocrine and neurological studies.
Somatostatin has clinical relevance as both a diagnostic marker and therapeutic target. Elevated somatostatin expression is observed in neuroendocrine tumors, while synthetic analogs such as octreotide are used to treat acromegaly, carcinoid syndrome, and other hormone secreting tumors. By applying SST antibody, scientists can investigate peptide hormone regulation, tumor biology, and therapeutic strategies targeting somatostatin pathways.
SST antibody from NSJ Bioreagents provides strong specificity for analyzing somatostatin biology. Its performance across applications ensures accurate detection of this important inhibitory peptide. -
UniProt
- P61278
抗原
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