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Recombinant Somatostatin 抗体

The 兔 单克隆 anti-Somatostatin antibody (Clone 31S68) (ABIN7882334) specifically detects Somatostatin in IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7882334
发货至: 中国
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中国
北京 101111
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Room 801-803
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Quick Overview for Recombinant Somatostatin 抗体 (ABIN7882334)

抗原

See all Somatostatin (SST) 抗体
Somatostatin (SST)

抗体类型

Recombinant Antibody

适用

  • 92
  • 54
  • 50
  • 4
  • 1
人, 小鼠, 大鼠

宿主

  • 87
  • 28
  • 2
  • 1
  • 1

克隆类型

  • 74
  • 45
单克隆

标记

  • 53
  • 16
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Somatostatin antibody is un-conjugated

应用范围

  • 70
  • 61
  • 20
  • 17
  • 16
  • 13
  • 9
  • 7
  • 6
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC)

克隆位点

31S68
  • 原理

    SST Antibody / Somatostatin

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human Somatostatin 28 was used as the immunogen for the SST antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the SST antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the SST antibody at -20oC.
  • 抗原

    Somatostatin (SST)

    别名

    SST

    物质类

    Chemical

    背景

    SST antibody detects somatostatin, a peptide hormone encoded by the SST gene. Somatostatin exists in two biologically active forms, somatostatin 14 and somatostatin 28, generated by alternative processing of a larger precursor. These peptides act as inhibitory hormones and neurotransmitters, regulating secretion of growth hormone, insulin, glucagon, and numerous gastrointestinal peptides. Somatostatin achieves its effects by binding to somatostatin receptors, a family of G protein coupled receptors expressed across many tissues.

    SST antibody is widely used in endocrinology, neuroscience, and cancer research. In the pituitary gland, somatostatin regulates growth hormone release. In the pancreas, it modulates insulin and glucagon secretion. In the gastrointestinal tract, it suppresses acid secretion and motility. By detecting somatostatin, researchers can evaluate how this peptide coordinates endocrine and paracrine regulation across multiple organ systems.

    Immunohistochemistry maps somatostatin producing cells in pancreatic islets, hypothalamus, and gastrointestinal mucosa. Immunofluorescence reveals somatostatin localization in neurons and endocrine cells, while ELISA enables quantitative analysis in serum or tissue extracts. These techniques make SST antibody a versatile tool for endocrine and neurological studies.

    Somatostatin has clinical relevance as both a diagnostic marker and therapeutic target. Elevated somatostatin expression is observed in neuroendocrine tumors, while synthetic analogs such as octreotide are used to treat acromegaly, carcinoid syndrome, and other hormone secreting tumors. By applying SST antibody, scientists can investigate peptide hormone regulation, tumor biology, and therapeutic strategies targeting somatostatin pathways.

    SST antibody from NSJ Bioreagents provides strong specificity for analyzing somatostatin biology. Its performance across applications ensures accurate detection of this important inhibitory peptide.

    UniProt

    P61278
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