TNNI1 抗体
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Quick Overview for TNNI1 抗体 (ABIN7882280)
抗原
See all TNNI1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TNNI1 Antibody / Troponin I slow skeletal muscle
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序列
- REAEKVRYLA ERIPTLQTR
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids REAEKVRYLAERIPTLQTR were used as the immunogen for the TNNI1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the TNNI1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the TNNI1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TNNI1 (Slow Skeletal Troponin I (TNNI1))
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别名
- TNNI1
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背景
- Troponin I, slow skeletal muscle is a protein that in humans is encoded by the TNNI1 gene. Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.
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UniProt
- P19237
抗原
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