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TNNI1 抗体

The 兔 多克隆 anti-TNNI1 antibody (ABIN7882280) specifically detects TNNI1 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7882280
发货至: 中国
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Quick Overview for TNNI1 抗体 (ABIN7882280)

抗原

See all TNNI1 抗体
TNNI1 (Slow Skeletal Troponin I (TNNI1))

适用

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宿主

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克隆类型

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多克隆

标记

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This TNNI1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 原理

    TNNI1 Antibody / Troponin I slow skeletal muscle

    序列

    REAEKVRYLA ERIPTLQTR

    纯化方法

    Antigen affinity purified

    免疫原

    Amino acids REAEKVRYLAERIPTLQTR were used as the immunogen for the TNNI1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the TNNI1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the TNNI1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    TNNI1 (Slow Skeletal Troponin I (TNNI1))

    别名

    TNNI1

    背景

    Troponin I, slow skeletal muscle is a protein that in humans is encoded by the TNNI1 gene. Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.

    UniProt

    P19237
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