Septin 5 抗体
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北京 101111
Quick Overview for Septin 5 抗体 (ABIN7882234)
抗原
See all Septin 5 (SEPT5) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SEPT5 Antibody / Septin 5
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序列
- HYENYRAHCI QQMTSKLTQD
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids HYENYRAHCIQQMTSKLTQD were used as the immunogen for the SEPT5 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SEPT5 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SEPT5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Septin 5 (SEPT5)
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别名
- SEPT5
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背景
- This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.
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UniProt
- Q99719
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途径
- Synaptic Vesicle Exocytosis
抗原
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