SELPLG 抗体
Our Local Distributor
北京 101111
Quick Overview for SELPLG 抗体 (ABIN7882228)
抗原
See all SELPLG 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
原理
- CD162 Antibody / PSGL-1 (azide and preservative free)
-
纯化方法
- Protein A/G affinity
-
免疫原
- Recombinant human PSGL-1 /CD162 protein was used as the immunogen for the CD162 antibody.
-
亚型
- IgM, kappa
-
-
-
-
应用备注
- Optimal dilution of the CD162 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- -20 °C
-
储存方法
- Aliquot the CD162 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- SELPLG (Selectin P Ligand (SELPLG))
-
别名
- CD162
-
背景
- CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.
-
UniProt
- Q14242
抗原
-