SARS-CoV-2 NSP4 抗体
Our Local Distributor
北京 101111
Quick Overview for SARS-CoV-2 NSP4 抗体 (ABIN7882201)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
原理
- SARS-CoV-2 NSP4 Antibody
-
纯化方法
- Affinity purified
-
免疫原
-
Amino acids HVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKAggggDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYC
YDTNVLEGSVAYESLRPDTRggggKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALN
DFSNSGSDVLYQPPQTSITSAVLQ were used as the immunogen for the SARS-CoV-2 NSP4 antibody. -
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the SARS-CoV-2 NSP4 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the SARS-CoV-2 NSP4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- SARS-CoV-2 NSP4 (SARS-CoV-2 Non-Structural Protein 4 (SARS-CoV-2 NSP4))
-
别名
- SARS-CoV-2 NSP4
-
物质类
- Viral Protein
-
背景
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ ORF1ab, the largest gene, contains overlapping open reading frames that encode polyproteins PP1ab and PP1a. The polyproteins are cleaved to yield 16 nonstructural proteins, NSP1-16. Production of the longer (PP1ab) or shorter protein (PP1a) depends on a -1 ribosomal frameshifting event. The proteins, based on similarity to other coronaviruses, include the papain-like proteinase protein (NSP3), 3C-like proteinase (NSP5), RNA-dependent RNA polymerase (NSP12, RdRp), helicase (NSP13, HEL), endoRNAse (NSP15), 2'-O-Ribose-Methyltransferase (NSP16) and other nonstructural proteins. SARS-CoV-2 nonstructural proteins are responsible for viral transcription, replication, proteolytic processing, suppression of host immune responses and suppression of host gene expression. The RNA-dependent RNA polymerase is a target of antiviral therapies.
-
UniProt
- P0DTC1
抗原
-