Recombinant S100A9 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant S100A9 抗体 (ABIN7882193)
抗原
See all S100A9 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
原理
- Recombinant S100A9 Antibody / MRP14 / Calgranulin B / Calprotectin (azide and preservative free)
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- An affinity purified monocyte membrane preparation was used as the immunogen for this recombinant S100A9 antibody.
-
亚型
- IgG1, kappa
-
-
-
-
应用备注
- Optimal dilution of the recombinant S100A9 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the recombinant S100A9 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- S100A9 (S100 Calcium Binding Protein A9 (S100A9))
-
别名
- S100A9
-
背景
- Recognizes the L1 or Calprotectin molecule, an intra-cytoplasmic antigen comprising of a 12 kDa alpha chain and a 14 kDa beta chain expressed by granulocytes, monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues, the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes), liver (Kupffer s cells), lung (alveolar macrophages), lymph nodes (free and fixed macrophages), spleen (free and fixed macrophages), bone marrow (fixed macrophages), serous fluids (pleural and peritoneal macrophages), skin (histiocytes, Langerhans's cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system, recognizing, engulfing and destroying many potential pathogens including bacteria, pathogenic protozoa, fungi and helminthes. This MAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections.
-
UniProt
- P06702
-
途径
- Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
抗原
-