Retinoid X Receptor gamma 抗体
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Quick Overview for Retinoid X Receptor gamma 抗体 (ABIN7882161)
抗原
See all Retinoid X Receptor gamma (RXRG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- RXR gamma Antibody / RXRG
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant human RXR gamma protein was used as the immunogen for the RXRG antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the RXR gamma antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the RXR gamma antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))
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别名
- RXR gamma
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背景
- Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARa, RARb and RARg, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXRa, RXRb and RXRg, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.
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UniProt
- P78347
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途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
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