Recombinant RAPGEF4 抗体
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北京 101111
Quick Overview for Recombinant RAPGEF4 抗体 (ABIN7882136)
抗原
See all RAPGEF4 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- RAPGEF4 Antibody / EPAC 2
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纯化方法
- Affinity chromatography
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免疫原
- A peptide sequence specific to Rap guanine nucleotide exchange factor 4 protein was used as the immunogen for the RAPGEF4 antibody.
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亚型
- IgG
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anti-Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4) (AA 1-110) antibody
RAPGEF4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C11 unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4) (AA 1-210) antibodyRAPGEF4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4) (AA 151-250) antibodyRAPGEF4 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4) (AA 1-1011) antibodyRAPGEF4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal dilution of the RAPGEF4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the RAPGEF4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RAPGEF4 (Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4))
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别名
- RAPGEF4
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背景
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Rap guanine nucleotide exchange factor 4 (RAPGEF4), also known as EPAC 2 (Exchange protein directly activated by cAMP 2), is a cAMP-regulated guanine nucleotide exchange factor that activates Rap1 and Rap2 small GTPases. Unlike protein kinase A, RAPGEF4 mediates cAMP signaling through a PKA-independent pathway, influencing processes such as cell adhesion, insulin secretion, and synaptic plasticity.
RAPGEF4 is expressed predominantly in the brain and endocrine tissues, where it contributes to learning and memory, hormone release, and neuronal signaling. Altered RAPGEF4 function has been implicated in metabolic disorders, neuropsychiatric conditions, and cancer, making it a significant target for biomedical research.
Using a high-quality RAPGEF4 antibody allows for sensitive detection in applications such as western blot, immunohistochemistry, and immunofluorescence. A RAPGEF4 antibody from NSJ Bioreagents ensures reliable and reproducible performance for studies in cAMP signaling, neuronal function, and endocrine regulation. Selecting the right RAPGEF4 antibody is essential for achieving accurate and consistent experimental results.
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UniProt
- Q8WZA2
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途径
- Hormone Transport, Smooth Muscle Cell Migration
抗原
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