PRC1 抗体
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北京 101111
Quick Overview for PRC1 抗体 (ABIN7882088)
抗原
See all PRC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PRC1 Antibody
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human PRC1 was used as the immunogen for the PRC1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PRC1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the PRC1 antibody at -20oC.
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- PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))
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别名
- PRC1
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背景
- Protein regulator of cytokinesis 1 (PRC1) is a key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression. [UniProt]
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UniProt
- O43663
抗原
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