Recombinant P4HTM 抗体
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北京 101111
Quick Overview for Recombinant P4HTM 抗体 (ABIN7882047)
抗原
See all P4HTM 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- P4HTM Antibody / HIF Prolyl Hydroxylases / HIFPH4
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纯化方法
- Affinity chromatography
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免疫原
- A synthetic peptide derived from human HIF Prolyl Hydroxylases was used as the immunogen for the P4HTM antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the P4HTM antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the P4HTM antibody at -20oC.
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- P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))
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别名
- P4HTM
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背景
- Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. [UniProt]
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UniProt
- Q9NXG6
抗原
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