Prolactin Receptor 抗体
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北京 101111
Quick Overview for Prolactin Receptor 抗体 (ABIN7882036)
抗原
See all Prolactin Receptor (PRLR) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Prolactin Receptor Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- Semi-purified human prolactin receptor was used as the immunogen for this anti-Prolactin Receptor antibody.
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亚型
- IgG1, kappa
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应用备注
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The optimal dilution of the anti-Prolactin Receptor antibody for each application should be determined by the researcher.
1. Staining of formalin/paraffin tissues requires digestion of tissue sections with Pepsin at 1 mg/mL Tris-HCl, pH 2.0 for 15 min at RT or 10 min at 37oC.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the anti-Prolactin Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Prolactin Receptor (PRLR)
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别名
- Prolactin Receptor
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背景
- It recognizes a protein of 70 kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.
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UniProt
- P16471
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途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus
抗原
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