KCNJ1 抗体
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Quick Overview for KCNJ1 抗体 (ABIN7882004)
抗原
See all KCNJ1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- KCNJ1 Antibody
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序列
- WYAVAYIHKD LPEFH
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纯化方法
- Affinity purified
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免疫原
- Amino acids WYAVAYIHKDLPEFH from the human protein were used as the immunogen for the KCNJ1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the KCNJ1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the KCNJ1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))
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别名
- KCNJ1
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背景
- Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P48048
抗原
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