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PHPT1 抗体

The 小鼠 单克隆 anti-PHPT1 antibody (Clone PHPT1-12053) (ABIN7881938) specifically detects PHPT1 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7881938
发货至: 中国
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Quick Overview for PHPT1 抗体 (ABIN7881938)

抗原

See all PHPT1 抗体
PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PHPT1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

PHPT1-12053
  • 原理

    PHPT1 Antibody / Phosphohistidine phosphatase 1

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant human 14 kDa phosphohistidine phosphatase protein was used as the immunogen for the PHPT1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the PHPT1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the PHPT1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))

    别名

    PHPT1

    背景

    PHPT1 (phosphohistidine phosphatase 1), also known as 14 kDa phosphohistidine phosphatase, is a 125 amino acid enzyme belonging to the Janus protein family. Existing as a monomer in the cytoplasm, PHPT1 is an EDTAinsensitive phosphohistidine phosphatase. First identified in human adrenal gland, PHPT1 is highly expressed in skeletal muscle and heart, with lower expression in liver, pancreas and kidney. Overexpression of PHPT1 leads to specific phosphohistidine phosphatase activity towards phosphopeptide I, with no activity detected towards phosphotyrosine, phosphothreonine and phosphoserine peptides. PHPT1 is highly conserved among species, suggesting that it serves an essential functional role.

    UniProt

    Q9NRX4

    途径

    Positive Regulation of Peptide Hormone Secretion
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