PHPT1 抗体
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北京 101111
Quick Overview for PHPT1 抗体 (ABIN7881936)
抗原
See all PHPT1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Phosphohistidine phosphatase 1 Antibody / PHPT1
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant human 14 kDa phosphohistidine phosphatase protein was used as the immunogen for the Phosphohistidine phosphatase 1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Phosphohistidine phosphatase 1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Phosphohistidine phosphatase 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))
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别名
- Phosphohistidine phosphatase 1
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背景
- PHPT1 (phosphohistidine phosphatase 1), also known as 14 kDa phosphohistidine phosphatase, is a 125 amino acid enzyme belonging to the Janus protein family. Existing as a monomer in the cytoplasm, PHPT1 is an EDTAinsensitive phosphohistidine phosphatase. First identified in human adrenal gland, PHPT1 is highly expressed in skeletal muscle and heart, with lower expression in liver, pancreas and kidney. Overexpression of PHPT1 leads to specific phosphohistidine phosphatase activity towards phosphopeptide I, with no activity detected towards phosphotyrosine, phosphothreonine and phosphoserine peptides. PHPT1 is highly conserved among species, suggesting that it serves an essential functional role.
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UniProt
- Q9NRX4
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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