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PITX2 抗体

This 兔 多克隆 antibody specifically detects PITX2 in WB. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN7881897
发货至: 中国
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Quick Overview for PITX2 抗体 (ABIN7881897)

抗原

See all PITX2 抗体
PITX2 (Paired-Like Homeodomain 2 (PITX2))

适用

  • 51
  • 7
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 44
  • 8

克隆类型

  • 45
  • 7
多克隆

标记

  • 29
  • 5
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PITX2 antibody is un-conjugated

应用范围

  • 40
  • 27
  • 9
  • 5
  • 5
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 原理

    PITX2 Antibody

    序列

    METNCRKLVS ACVQLGVQPA AVECLFSKDS EIKK

    纯化方法

    Affinity purified

    免疫原

    Amino acids METNCRKLVSACVQLGVQPAAVECLFSKDSEIKK were used as the immunogen for the PITX2 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the PITX2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the PITX2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    PITX2 (Paired-Like Homeodomain 2 (PITX2))

    别名

    PITX2

    背景

    Paired-like homeodomain transcription factor 2 also known as pituitary homeobox 2 is a protein that in humans is encoded by the PITX2 gene. It is mapped to 4q25. This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described.

    UniProt

    Q99697

    途径

    Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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