Recombinant NUP155 抗体
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北京 101111
Quick Overview for Recombinant NUP155 抗体 (ABIN7881861)
抗原
See all NUP155 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- NUP155 Antibody / Nucleoporin 155
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human NUP155 was used as the immunogen for the NUP155 antibody.
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亚型
- IgG
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anti-Nucleoporin 155kDa (NUP155) (AA 1154-1379) antibody
NUP155 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 155kDa (NUP155) antibodyKD Validated NUP155 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2010 unconjugated Recombinant Antibody
anti-Nucleoporin 155kDa (NUP155) (AA 9-38), (N-Term) antibodyNUP155 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB20193 unconjugated
anti-Nucleoporin 155kDa (NUP155) (N-Term) antibodyNUP155 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 155kDa (NUP155) (AA 1102-1391) antibodyNUP155 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 155kDa (NUP155) (AA 796-845) antibodyNUP155 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 155kDa (NUP155) (N-Term) antibodyNUP155 适用: 人, 犬, 兔, 豚鼠, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 155kDa (NUP155) (N-Term) antibodyNUP155 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 155kDa (NUP155) (AA 1341-1391) antibodyNUP155 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the NUP155 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the NUP155 antibody at -20oC.
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- NUP155 (Nucleoporin 155kDa (NUP155))
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别名
- NUP155
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背景
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NUP155 antibody recognizes nucleoporin 155, a major component of the nuclear pore complex encoded by the NUP155 gene. Nuclear pore complexes are large protein assemblies embedded in the nuclear envelope that regulate transport of molecules between the nucleus and cytoplasm. NUP155 contributes to the structural integrity of the pore and facilitates trafficking of RNAs, proteins, and signaling molecules.
NUP155 antibody is commonly used in studies of nucleocytoplasmic transport and nuclear architecture. The protein is particularly important for maintaining nuclear envelope stability and selective transport of cargo. Defects in NUP155 impair nuclear pore complex assembly and disrupt gene regulation by altering nucleo cytoplasmic communication.
The antibody is suitable for western blotting, immunohistochemistry, immunofluorescence, and flow cytometry. In western blot assays, NUP155 antibody recognizes protein bands corresponding to the expected molecular weight. Immunohistochemistry shows localization at the nuclear envelope, while immunofluorescence provides fine resolution of subnuclear distribution. These applications make NUP155 antibody versatile for research in molecular biology and cell signaling.
Clinical research has linked NUP155 mutations to atrial fibrillation and sudden cardiac death. The connection underscores the importance of nuclear pore complexes beyond basic transport, showing that nuclear envelope proteins contribute to cardiac rhythm and function. By detecting NUP155, researchers can explore how mutations or altered expression influence disease progression.
Nucleoporins, including NUP155, are increasingly recognized as regulators of gene expression. Their roles extend to chromatin organization, DNA repair, and signal transduction. Dysregulation of nucleoporins has been linked to cancer and developmental disorders. NUP155 antibody provides a tool to investigate how nuclear pore function impacts diverse biological processes.
NUP155 antibody from NSJ Bioreagents provides reliable specificity for analyzing nuclear pore biology, disease pathogenesis, and cellular communication. It is a valuable reagent for laboratories studying nuclear transport and gene regulation. -
UniProt
- O75694
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途径
- Protein targeting to Nucleus
抗原
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