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MSTN 抗体

The 兔 多克隆 anti-MSTN antibody is suitable to detect MSTN in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN7881742
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MSTN 抗体 (ABIN7881742)

抗原

See all MSTN 抗体
MSTN (Myostatin (MSTN))

适用

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人, 小鼠, 大鼠

宿主

  • 101
  • 22
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克隆类型

  • 109
  • 25
多克隆

标记

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This MSTN antibody is un-conjugated

应用范围

  • 100
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Western Blotting (WB)
  • 原理

    GDF8 Antibody / Myostatin

    序列

    SGECEFVFLQ KYPH

    纯化方法

    Affinity purified

    免疫原

    Amino acids SGECEFVFLQKYPH from the human protein were used as the immunogen for the GDF8 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the GDF8 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the GDF8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    MSTN (Myostatin (MSTN))

    别名

    GDF8

    背景

    Myostatin (also known as growth differentiation factor 8, abbreviated GDF-8) is a myokine, a protein produced and released by myocytes that acts on muscle cells' autocrine function to inhibit myogenesis: muscle cell growth and differentiation. In humans it is encoded by the MSTN gene. This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals.

    UniProt

    O14793
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