MYH11 抗体
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北京 101111
Quick Overview for MYH11 抗体 (ABIN7881733)
抗原
See all MYH11 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- SM-MHC Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- Human uterus extract was used as the immunogen for the SM-MHC antibody.
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亚型
- IgG1, kappa
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应用备注
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The stated application concentrations are suggested starting amounts. Optimal dilution of the SM-MHC antibody should be determined by the researcher.
1. Staining of formalin/paraffin tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the SM-MHC antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))
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别名
- SM-MHC
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背景
- Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
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UniProt
- P35749
抗原
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