MYOD1 抗体
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北京 101111
Quick Overview for MYOD1 抗体 (ABIN7881721)
抗原
See all MYOD1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- MyoD1 Antibody
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant mouse MyoD1 protein was used as the immunogen for the MyoD1 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the MyoD1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MyoD1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MYOD1 (Myogenic Differentiation 1 (MYOD1))
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别名
- MyoD1
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背景
- Recognizes a phosphor-protein of 45 kDa, identified as MyoD1. The epitope of this mAb maps between amino acid 180-189 in the C-terminal of mouse MyoD1 protein. It does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas.
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UniProt
- P15172
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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