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MBP 抗体

The 大鼠 单克隆 anti-MBP antibody is suitable to detect MBP in samples from 人. It has been validated for WB 和 IHC (p).
产品编号 ABIN7881703
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MBP 抗体 (ABIN7881703)

抗原

See all MBP 抗体
MBP (Myelin Basic Protein (MBP))

适用

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宿主

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大鼠

克隆类型

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单克隆

标记

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This MBP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

MBP-4274
  • 原理

    Myelin Basic Protein Antibody (azide and preservative free)

    序列

    GILDSIGRFF GGDRG

    纯化方法

    Protein G affinity chromatography

    免疫原

    Amino acids GILDSIGRFFGGDRG from the human protein were used as the immunogen for the Myelin Basic Protein antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the Myelin Basic Protein antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Myelin Basic Protein antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    MBP (Myelin Basic Protein (MBP))

    别名

    Myelin Basic Protein

    背景

    Myelin basic protein (MBP) is the second most abundant protein in central nervous system (CNS) myelin: it comprises 30 % of the total protein and about 10 % of the dry weight of myelin. It is the only structural protein found so far to be essential for formation of CNS myelin, and has been called the executive molecule of myelin . MBP can interact with a number of polyanionic proteins including actin, tubulin, calmodulin, and clathrin, and negatively charged lipids, and acquires structure on binding to them. It may act as a membrane actin-binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocytes and tight junctions in myelin. MBP may be applicable as a marker for oligodendrogliomas. MBP/4274 recognizes an epitope in the 36-50 region of MBP, useful in clinical diagnosis to detect MBP levels or myelination in human MBP.

    UniProt

    P02686
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