MBP 抗体
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北京 101111
Quick Overview for MBP 抗体 (ABIN7881703)
抗原
See all MBP 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Myelin Basic Protein Antibody (azide and preservative free)
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序列
- GILDSIGRFF GGDRG
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纯化方法
- Protein G affinity chromatography
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免疫原
- Amino acids GILDSIGRFFGGDRG from the human protein were used as the immunogen for the Myelin Basic Protein antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the Myelin Basic Protein antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Myelin Basic Protein antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- MBP (Myelin Basic Protein (MBP))
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别名
- Myelin Basic Protein
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背景
- Myelin basic protein (MBP) is the second most abundant protein in central nervous system (CNS) myelin: it comprises 30 % of the total protein and about 10 % of the dry weight of myelin. It is the only structural protein found so far to be essential for formation of CNS myelin, and has been called the executive molecule of myelin . MBP can interact with a number of polyanionic proteins including actin, tubulin, calmodulin, and clathrin, and negatively charged lipids, and acquires structure on binding to them. It may act as a membrane actin-binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocytes and tight junctions in myelin. MBP may be applicable as a marker for oligodendrogliomas. MBP/4274 recognizes an epitope in the 36-50 region of MBP, useful in clinical diagnosis to detect MBP levels or myelination in human MBP.
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UniProt
- P02686
抗原
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