MBP 抗体
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北京 101111
Quick Overview for MBP 抗体 (ABIN7881700)
抗原
See all MBP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Myelin Basic Protein Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- A synthetic peptide corresponding to the amino acids surrounding phosphorylated threonine 98 were used as the immunogen for the Myelin Basic Protein antibody.
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亚型
- IgG2a
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anti-Myelin Basic Protein (MBP) antibody
MBP 适用: 人 IHC, ICC, ELISA, FACS 宿主: 小鼠 Monoclonal 2H9 unconjugated
anti-Myelin Basic Protein (MBP) antibodyKD Validated MBP 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB1215 unconjugated Recombinant Antibody
anti-Myelin Basic Protein (MBP) (AA 135-190) antibodyMBP 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Myelin Basic Protein (MBP) antibodyMBP 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myelin Basic Protein (MBP) (AA 150-250) antibodyMBP 适用: 人 IHC 宿主: 兔 Monoclonal 390R unconjugated Recombinant Antibody
anti-Myelin Basic Protein (MBP) (AA 220-301) antibodyMBP 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Myelin Basic Protein (MBP) (AA 18-222) antibodyMBP 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Myelin Basic Protein (MBP) (AA 182-197) antibodyMBP 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myelin Basic Protein (MBP) (AA 130-136) antibodyMBP 适用: 人, 小鼠, 大鼠, 兔, 绵羊, 山羊, 灵长类 WB, IHC, ELISA, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal unconjugated
anti-Myelin Basic Protein (MBP) (AA 220-301) antibodyMBP 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C13 unconjugated
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应用备注
- Optimal dilution of the Myelin Basic Protein antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Myelin Basic Protein antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- MBP (Myelin Basic Protein (MBP))
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别名
- Myelin Basic Protein
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背景
- Myelin basic protein (MBP) is the second most abundant protein in central nervous system (CNS) myelin: it comprises 30 % of the total protein and about 10 % of the dry weight of myelin. It is the only structural protein found so far to be essential for formation of CNS myelin, and has been called the executive molecule of myelin . MBP can interact with a number of polyanionic proteins including actin, tubulin, calmodulin, and clathrin, and negatively charged lipids, and acquires structure on binding to them. It may act as a membrane actin-binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocytes and tight junctions in myelin. MBP may be applicable as a marker for oligodendrogliomas. Phosphorylation been shown to decrease its ability to aggregate lipid vesicles and consequently destabilising the compact structure ofmyelin, a destruction that has been observed in demyelinating diseases such as Multiple Sclerosis. MBP/4276 is a useful detector of phosphorylated MBP by binding to Thr98 of human MBP in the phosphorylated state.
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UniProt
- P02686
抗原
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