MAL 抗体
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北京 101111
Quick Overview for MAL 抗体 (ABIN7881698)
抗原
See all MAL 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MAL Antibody / Myelin and lymphocyte protein
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序列
- HAVFSLIRWK SS
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纯化方法
- Affinity purified
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免疫原
- Amino acids HAVFSLIRWKSS from the human protein were used as the immunogen for the MAL antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the MAL antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MAL antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))
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别名
- MAL
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背景
- Myelin and lymphocyte protein is a protein that in humans is encoded by the MAL gene. The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.
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UniProt
- P21145
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途径
- Asymmetric Protein Localization
抗原
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