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Moesin 抗体

The 小鼠 单克隆 anti-Moesin antibody (Clone SPM562) (ABIN7881659) specifically detects Moesin in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7881659
发货至: 中国
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Quick Overview for Moesin 抗体 (ABIN7881659)

抗原

See all Moesin (MSN) 抗体
Moesin (MSN)

适用

  • 111
  • 77
  • 43
  • 8
  • 5
  • 5
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  • 4
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  • 1
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宿主

  • 77
  • 40
  • 1
小鼠

克隆类型

  • 61
  • 56
单克隆

标记

  • 67
  • 8
  • 4
  • 3
  • 3
  • 3
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  • 3
  • 3
  • 2
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  • 2
  • 2
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  • 2
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  • 1
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This Moesin antibody is un-conjugated

应用范围

  • 97
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  • 38
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  • 1
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

SPM562
  • 原理

    Moesin Antibody

    纯化方法

    Protein G affinity chromatography

    免疫原

    Recombinant human protein was used as the immunogen for this Moesin antibody.

    亚型

    IgG1, kappa
  • 应用备注

    The optimal dilution of the Moesin antibody for each application should be determined by the researcher.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Moesin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Moesin (MSN)

    别名

    Moesin

    背景

    Recognizes 78 kDa moesin protein. Moesin, a member of the Talin-4.1 superfamily, is a linking protein of the submembraneous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.

    UniProt

    P26038

    途径

    Asymmetric Protein Localization
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