MFGE8 抗体
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北京 101111
Quick Overview for MFGE8 抗体 (ABIN7881640)
抗原
See all MFGE8 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MFG-E8 Antibody / Lactadherin / Milk Fat Globule
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序列
- FKVAYSLNGH EFDFIHDVNK KHKE
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids FKVAYSLNGHEFDFIHDVNKKHKE from the human protein were used as the immunogen for the MFG-E8 antibody.
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亚型
- IgG
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anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) (AA 1-200) antibody
MFGE8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) antibodyMFGE8 适用: 人 IHC 宿主: 小鼠 Monoclonal MFG-06 unconjugated
anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) antibodyMFGE8 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) (AA 73-421) antibodyMFGE8 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) (AA 159-417) antibodyMFGE8 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) antibodyMFGE8 适用: 人 IHC, FACS, IF 宿主: 小鼠 Monoclonal EDM45 unconjugated
anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) antibodyCarrier-free MFGE8 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal MFG-06 unconjugated
anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) antibodyCarrier-free MFGE8 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal SPM291 unconjugated
anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) (AA 1-387) antibodyMFGE8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) (AA 1-387) antibodyMFGE8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal dilution of the MFG-E8 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MFG-E8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))
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别名
- MFG-E8
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背景
- MFGE8 (Milk Fat Globule-Egf Factor 8), also called as Lactadherin or SED1, is a protein which in humans is encoded by the MFGE8 gene. Mfge8 is secreted protein found in vertebrates, including mammals as well as birds. By fluorescence in situ hybridization, Collins et al.(1997) mapped the MFGE8 gene to chromosome 15q25. Hanayama et al.(2002) found that MFGE8 is a factor that links apoptotic cells to phagocytes. MFGE8 specifically bound to apoptotic cells by recognizing aminophospholipids such as phosphatidylserine. MFGE8, when engaged by phospholipids, bound to cells via its RGD motif. It bound particularly strongly to cells expressing alpha-V-beta-3 integrin. Bu et al.(2007) showed that Mfge8 was expressed in intestinal lamina propria macrophages in mice. Using a wound-healing assay, they showed that Mfge8 promoted migration of intestinal epithelial cells through a PKC-epsilon(PRKCE)-dependent mechanism.
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UniProt
- Q08431
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途径
- SARS-CoV-2 Protein Interactome
抗原
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