MBD3 抗体
Our Local Distributor
北京 101111
Quick Overview for MBD3 抗体 (ABIN7881628)
抗原
See all MBD3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- MBD3 Antibody
-
纯化方法
- Affinity purified
-
免疫原
- A synthetic peptide specific to human MBD3 was used as the immunogen for the MBD3 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the MBD3 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store the MBD3 antibody at -20oC.
-
-
- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
-
别名
- MBD3
-
背景
- DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. The MBD3 gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. [RefSeq]
-
UniProt
- O95983
-
途径
- Chromatin Binding
抗原
-