Recombinant MSRB3 抗体
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Quick Overview for Recombinant MSRB3 抗体 (ABIN7881624)
抗原
See all MSRB3 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- MSRB3 Antibody / Methionine sulfoxide reductase B3
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human MSRB3 was used as the immunogen for the MSRB3 antibody.
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亚型
- IgG
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anti-Methionine Sulfoxide Reductase B3 (MSRB3) antibody
MSRB3 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Methionine Sulfoxide Reductase B3 (MSRB3) (AA 1-185) antibodyMSRB3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Methionine Sulfoxide Reductase B3 (MSRB3) (AA 1-185) antibodyMSRB3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methionine Sulfoxide Reductase B3 (MSRB3) (AA 1-185) antibodyMSRB3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Methionine Sulfoxide Reductase B3 (MSRB3) (AA 1-185) antibodyMSRB3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Methionine Sulfoxide Reductase B3 (MSRB3) antibodyMSRB3 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Methionine Sulfoxide Reductase B3 (MSRB3) antibodyMSRB3 适用: 人 WB 宿主: 兔 Monoclonal 24GB3550 unconjugated Recombinant Antibody
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应用备注
- Optimal dilution of the MSRB3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the MSRB3 antibody at -20oC.
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- MSRB3 (Methionine Sulfoxide Reductase B3 (MSRB3))
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别名
- MSRB3
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背景
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MSRB3 antibody detects methionine sulfoxide reductase B3, a repair enzyme encoded by the MSRB3 gene. MSRB3 belongs to the methionine sulfoxide reductase family, which reduces oxidized methionine residues back to methionine. By repairing oxidatively damaged proteins, MSRB3 contributes to redox regulation, protein quality control, and cellular defense against oxidative stress. MSRB3 exists in two isoforms localized to mitochondria and endoplasmic reticulum, reflecting its broad role in maintaining proteostasis.
MSRB3 antibody is widely applied in studies of redox biology, aging, and hearing research. Mutations in MSRB3 cause autosomal recessive nonsyndromic hearing loss due to impaired protection of auditory cells against oxidative damage. By detecting MSRB3, researchers can explore how oxidative stress contributes to sensory degeneration and how protein repair mechanisms maintain tissue health.
In western blot assays, MSRB3 antibody detects protein bands of expected molecular weight in mitochondrial and ER fractions. Immunohistochemistry highlights expression in cochlea, brain, and liver, while immunofluorescence demonstrates subcellular localization to mitochondria and ER networks. These applications provide detailed analysis of MSRB3 distribution and function.
MSRB3 contributes to cellular stress resistance by repairing oxidized methionine in metabolic and structural proteins. Its protective functions extend to aging, neurodegeneration, and metabolic disease. Dysregulation of MSRB3 has been associated with reduced stress tolerance, enhanced apoptosis, and impaired organ function. By applying MSRB3 antibody, scientists can investigate therapeutic strategies aimed at enhancing protein repair pathways.
MSRB3 antibody from NSJ Bioreagents provides strong specificity for analyzing methionine repair mechanisms and oxidative stress responses. Its reliability across multiple assays makes it a critical reagent for studying redox regulation, aging, and sensory biology. -
UniProt
- Q8IXL7
抗原
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