NG2 抗体
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北京 101111
Quick Overview for NG2 抗体 (ABIN7881590)
抗原
See all NG2 (MCSP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CSPG4 Antibody / NG2
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纯化方法
- Protein G affinity chromatography
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免疫原
- A 375P cells crude extract was used as the immunogen for this CSPG4 antibody
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亚型
- IgG1, kappa
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anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) (AA 2247-2308) antibody
MCSP 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 7G4E5 unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) (AA 1919-2258) antibodyMCSP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) (AA 1950-2210) antibodyMCSP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) antibodyKD Validated MCSP 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3470 unconjugated Recombinant Antibody
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) (AA 559-776) antibodyMCSP 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 6# unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) (AA 2247-2308) antibodyMCSP 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) (AA 1950-2210) antibodyMCSP 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) antibodyMicroarray verified MCSP 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB300756 unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) antibodyMicroarray verified MCSP 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB41136 unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) antibodyMCSP 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
- Optimal dilution of the CSPG4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the CSPG4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
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别名
- CSPG4
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背景
- Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades. [UniProt]
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UniProt
- Q6UVK1
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途径
- Glycosaminoglycan Metabolic Process
抗原
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