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L1CAM 抗体

The 小鼠 单克隆 anti-L1CAM antibody (Clone SPM275) (ABIN7881449) specifically detects L1CAM in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7881449
发货至: 中国
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Quick Overview for L1CAM 抗体 (ABIN7881449)

抗原

See all L1CAM 抗体
L1CAM (L1 Cell Adhesion Molecule (L1CAM))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This L1CAM antibody is un-conjugated

应用范围

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ELISA

质量等级

Carrier-free

克隆位点

SPM275
  • 原理

    L1CAM Antibody / NCAM-L1 / CD171 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Homogenous suspension of 16-week human fetal brain cells were used as the immunogen for the L1CAM antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the L1CAM antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the L1CAM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    L1CAM (L1 Cell Adhesion Molecule (L1CAM))

    别名

    L1CAM

    背景

    Recognizes a cell surface protein of 220-240 kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius), 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs), and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.

    UniProt

    P32004

    途径

    Synaptic Membrane
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