Keratin Basic 抗体
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北京 101111
Quick Overview for Keratin Basic 抗体 (ABIN7881436)
抗原
See all Keratin Basic 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Basic Cytokeratin Antibody (azide and preservative free)
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纯化方法
- Protein G purified
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免疫原
- Solubilized cytokeratin extract from human stratum corneum was used as the immunogen.
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亚型
- IgG1
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anti-Keratin Basic antibody
Carrier-free 适用: 人, 大鼠 IHC (p) 宿主: 小鼠 Monoclonal KRTH-1076 unconjugated
anti-Keratin Basic antibody适用: 人, 大鼠, 小鼠 WB, IF, IHC, FACS 宿主: 小鼠 Monoclonal SPM591 unconjugated
anti-Keratin Basic antibody适用: 人 IHC (p) 宿主: 兔 Monoclonal KRTH-1576R unconjugated Recombinant Antibody
anti-Keratin Basic antibodyCarrier-free 适用: 人 IHC (p) 宿主: 兔 Monoclonal KRTH-1576R unconjugated Recombinant Antibody
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应用备注
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Differences in protocols and secondaries may cause the Basic Cytokeratin antibody to need titering for optimal performance.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Basic Cytokeratin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Keratin Basic
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别名
- Basic Cytokeratin
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背景
- This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67 kDa (CK1), 64 kDa (CK3), 59 kDa (CK4), 58 kDa (CK5), 56 kDa (CK6), 52 kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50, 48, 46, 45, and 40 kDa. This MAb recognizes the 65-67, 64, 59, 58, 56, and 52 kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. SPM115/SPM116 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
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UniProt
- Q01546
抗原
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