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Recombinant KRT17 抗体

The 兔 单克隆 anti-KRT17 antibody is suitable to detect KRT17 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7881373
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant KRT17 抗体 (ABIN7881373)

抗原

See all KRT17 抗体
KRT17 (Keratin 17 (KRT17))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This KRT17 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

KRT17-8346R
  • 原理

    Recombinant Keratin 17 Antibody / Cytokeratin 17

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant fragment of human KRT17 protein was used as the immunogen for the recombinant Keratin 17 antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the recombinant Keratin 17 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant Keratin 17 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    KRT17 (Keratin 17 (KRT17))

    别名

    Keratin 17

    背景

    Cytokeratin 17 is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glands such as mammary, sweat and salivary. It is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered as epithelial stem cell marker because CK17 Ab marks basal cell differentiation. CK17 is expressed in SCLC much higher than in LADC. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course.

    UniProt

    Q04695
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