Recombinant Cytokeratin 13 抗体
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北京 101111
Quick Overview for Recombinant Cytokeratin 13 抗体 (ABIN7881355)
抗原
See all Cytokeratin 13 (KRT13) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Recombinant KRT13 Antibody / Cytokeratin 13 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Esophageal keratins of rabbit origin were used as the immunogen for the recombinant KRT13 antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the recombinant KRT13 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant KRT13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))
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别名
- KRT13
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背景
- Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs)that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation, which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 13 belongs to the intermediate filament family and is a heterotetramer of two type I acidic and two type II basic keratins. It is generally associated with Cytokeratin 4. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder which predominantly affects noncornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa.
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UniProt
- P13646
抗原
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