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Recombinant Cytokeratin 13 抗体

This 兔 单克隆 antibody specifically detects Cytokeratin 13 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7881354
发货至: 中国
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Quick Overview for Recombinant Cytokeratin 13 抗体 (ABIN7881354)

抗原

See all Cytokeratin 13 (KRT13) 抗体
Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

抗体类型

Recombinant Antibody

适用

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宿主

  • 81
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克隆类型

  • 70
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单克隆

标记

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This Cytokeratin 13 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

KRT13-8577R
  • 原理

    CK13 Antibody / Cytokeratin 13

    纯化方法

    Protein A affinity

    免疫原

    Esophageal keratins of rabbit origin were used as the immunogen for the CK13 antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the CK13 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the CK13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

    别名

    CK13

    背景

    Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation, which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 13 belongs to the intermediate filament family and is a heterotetramer of two type I acidic and two type II basic keratins. It is generally associated with Cytokeratin 4. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder which predominantly affects noncornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa.

    UniProt

    P13646
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