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Recombinant Cytokeratin 13 抗体

The 兔 单克隆 anti-Cytokeratin 13 antibody (Clone KRT13-8577R) (ABIN7881353) specifically detects Cytokeratin 13 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7881353
发货至: 中国
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Quick Overview for Recombinant Cytokeratin 13 抗体 (ABIN7881353)

抗原

See all Cytokeratin 13 (KRT13) 抗体
Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This Cytokeratin 13 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

KRT13-8577R
  • 原理

    CK13 Antibody / Cytokeratin 13 (azide and preservative free)

    纯化方法

    Protein A affinity

    免疫原

    Esophageal keratins of rabbit origin were used as the immunogen for the CK13 antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the CK13 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the CK13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

    别名

    CK13

    背景

    Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation, which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 13 belongs to the intermediate filament family and is a heterotetramer of two type I acidic and two type II basic keratins. It is generally associated with Cytokeratin 4. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder which predominantly affects noncornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa.

    UniProt

    P13646
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