KPNA1 抗体
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北京 101111
Quick Overview for KPNA1 抗体 (ABIN7881342)
抗原
See all KPNA1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- KPNA1 Antibody / Importin alpha 5 / SRP1
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序列
- VITSDMIEMI FSKSPEQQLS ATQKFRKL
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纯化方法
- Affinity purified
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免疫原
- Amino acids VITSDMIEMIFSKSPEQQLSATQKFRKL from the human protein were used as the immunogen for the KPNA1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the KPNA1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the KPNA1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))
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别名
- KPNA1
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背景
- Importin subunit alpha 5 is a protein that in humans is encoded by the KPNA1 gene. The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.
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UniProt
- P52294
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途径
- M Phase, Protein targeting to Nucleus
抗原
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