IL-25 抗体
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北京 101111
Quick Overview for IL-25 抗体 (ABIN7881298)
抗原
See all IL-25 (IL25) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- IL-25 Antibody / IL-17E (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant protein fragment was used as the immunogen for the IL-25 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the IL-25 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the IL-25 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IL-25 (IL25) (Interleukin 25 (IL25))
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别名
- IL-25
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背景
- Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. Interleukin-17 (IL-17) and its cognate receptor, IL-17R, are an example of such a cytokine receptor pair. Originally identified as a rodent cDNA termed CTLA8, IL-17 is capable of inducing the secretion of IL-6 and IL-8 and augmenting the expression of ICAM-1 in human fibroblast cultures. The IL-17 protein exhibits a striking degree of homology with the HSV-13 protein which mimics its function. The IL-17 receptor is a type I transmembrane protein 864 amino acids in length that is highly expressed in spleen and kidney.
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UniProt
- Q9H293
抗原
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