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IFNA1 抗体

This 小鼠 单克隆 antibody specifically detects IFNA1 in WB 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7881251
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IFNA1 抗体 (ABIN7881251)

抗原

See all IFNA1 抗体
IFNA1 (Interferon, alpha 1 (IFNA1))

适用

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宿主

  • 42
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小鼠

克隆类型

  • 44
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单克隆

标记

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This IFNA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

IFNA-6689
  • 原理

    Interferon alpha 1 Antibody / IFNA1

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant human IFNA1 protein was used as the immunogen for the Interferon alpha 1 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the Interferon alpha 1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Interferon alpha 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    IFNA1 (Interferon, alpha 1 (IFNA1))

    别名

    Interferon alpha 1

    背景

    This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.Produced by macrophages, IFN-alphas have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase

    UniProt

    P01562

    途径

    JAK/STAT Signaling, Hepatitis C
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