IFNA1 抗体
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北京 101111
Quick Overview for IFNA1 抗体 (ABIN7881250)
抗原
See all IFNA1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Interferon alpha 1 Antibody / IFNA1 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant human IFNA1 protein was used as the immunogen for the Interferon alpha 1 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the Interferon alpha 1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the Interferon alpha 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IFNA1 (Interferon, alpha 1 (IFNA1))
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别名
- Interferon alpha 1
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背景
- This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.Produced by macrophages, IFN-alphas have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase
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UniProt
- P01562
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途径
- JAK/STAT Signaling, Hepatitis C
抗原
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