Recombinant INMT 抗体
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北京 101111
Quick Overview for Recombinant INMT 抗体 (ABIN7881168)
抗原
See all INMT 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- INMT Antibody / TEMT
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human TEMT was used as the immunogen for the INMT antibody.
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亚型
- IgG
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anti-Indolethylamine N-Methyltransferase (INMT) (AA 1-263) antibody
INMT 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Indolethylamine N-Methyltransferase (INMT) antibodyINMT 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Indolethylamine N-Methyltransferase (INMT) antibodyINMT 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2160 unconjugated Recombinant Antibody
anti-Indolethylamine N-Methyltransferase (INMT) (AA 101-128) antibodyINMT 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB26875 unconjugated
anti-Indolethylamine N-Methyltransferase (INMT) (AA 174-263) antibodyINMT 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Indolethylamine N-Methyltransferase (INMT) antibodyINMT 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Indolethylamine N-Methyltransferase (INMT) (N-Term) antibodyINMT 适用: 人, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Indolethylamine N-Methyltransferase (INMT) (N-Term) antibodyINMT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Indolethylamine N-Methyltransferase (INMT) antibodyINMT 适用: 人 WB 宿主: 兔 Monoclonal 23GB2155 unconjugated Recombinant Antibody
anti-Indolethylamine N-Methyltransferase (INMT) (N-Term) antibodyINMT 适用: 人, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the INMT antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the INMT antibody at -20oC.
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- INMT (Indolethylamine N-Methyltransferase (INMT))
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别名
- INMT
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背景
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INMT antibody detects indolethylamine N methyltransferase, also known as TEMT, encoded by the INMT gene. INMT is a cytosolic enzyme that catalyzes the N methylation of tryptamine and other indolethylamines, producing N N dimethyltryptamine and related metabolites. This activity places INMT in pathways regulating biogenic amine metabolism, neurotransmitter balance, and endogenous hallucinogen production. INMT is expressed in liver, lung, brain, and peripheral tissues, suggesting roles in both metabolic clearance and neuroregulation.
INMT antibody is widely applied in neurobiology, pharmacology, and metabolism research. INMT contributes to serotonin and tryptamine metabolism and has been proposed as the enzyme responsible for biosynthesis of endogenous dimethyltryptamine in mammals. By detecting INMT, researchers can examine its distribution, activity, and regulation in diverse tissues.
Western blotting with INMT antibody detects enzyme expression in liver and brain samples. Immunohistochemistry maps expression in neuronal and peripheral tissues, while immunofluorescence highlights cytoplasmic localization within cells. These approaches provide powerful tools for characterizing INMT biology.
INMT has clinical and pharmacological significance. Altered expression has been linked to pulmonary hypertension, schizophrenia, and other neuropsychiatric conditions. Genetic polymorphisms in INMT influence enzyme activity and metabolic profiles. By applying INMT antibody, scientists can explore how changes in tryptamine metabolism contribute to disease and therapeutic response.
INMT also participates in xenobiotic metabolism by methylating exogenous compounds. Its role in detoxification pathways expands its relevance to pharmacology and toxicology. INMT antibody supports studies into how methyltransferases regulate chemical balance in the body.
Research continues to evaluate INMT in neurological function, where dimethyltryptamine has been implicated in altered states of consciousness and potential therapeutic applications. Investigating INMT expression with antibody based methods provides insights into both fundamental biology and emerging areas of translational research.
INMT antibody from NSJ Bioreagents provides reliable specificity for detecting indolethylamine N methyltransferase. Its performance across assays ensures accurate results in metabolism, neuroscience, and pharmacology. -
UniProt
- O95050
抗原
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