IMPDH2 抗体
Our Local Distributor
北京 101111
Quick Overview for IMPDH2 抗体 (ABIN7881162)
抗原
See all IMPDH2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Inosine-5'-monophosphate dehydrogenase 2 Antibody / IMPDH2
-
序列
- VVLSPKDRVR DVFEAKARH
-
纯化方法
- Antigen affinity purified
-
免疫原
- Amino acids VVLSPKDRVRDVFEAKARH were used as the immunogen for the Inosine-5'-monophosphate dehydrogenase 2 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the Inosine-5'-monophosphate dehydrogenase 2 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the Inosine-5'-monophosphate dehydrogenase 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
-
别名
- Inosine-5'-monophosphate dehydrogenase 2
-
背景
- Inosine-5'-monophosphate dehydrogenase 2, also known as IMP dehydrogenase 2, is an enzyme that in humans is encoded by the IMPDH2 gene. This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
-
UniProt
- P12268
-
途径
- Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interactome
抗原
-