HSD17B2 抗体
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北京 101111
Quick Overview for HSD17B2 抗体 (ABIN7881141)
抗原
See all HSD17B2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- HSD17B2 Antibody
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序列
- IYDYFAKRHF GQDK
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纯化方法
- Affinity purified
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免疫原
- Amino acids IYDYFAKRHFGQDK from the human protein were used as the immunogen for the HSD17B2 antibody.
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亚型
- IgG
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anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 118-387) antibody
HSD17B2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 1-387) antibodyHSD17B2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 373-387) antibodyHSD17B2 适用: 人 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) antibodyHSD17B2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (C-Term) antibodyHSD17B2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 265-294) antibodyHSD17B2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26219 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 1-387) antibodyHSD17B2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 118-387) antibodyHSD17B2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) antibodyHSD17B2 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 151-250) antibodyHSD17B2 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the HSD17B2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the HSD17B2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- HSD17B2 (Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2))
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别名
- HSD17B2
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背景
- HSD17B2 (17-BETA-HYDROXYSTEROID DEHYDROGENASE II), also called 17-BETA-HSD II, is an anzyme which have 387 amino acids with a predicted molecular weight of 42,782 and associate with the membranes of the endoplasmic reticulum. Its Cytogenetic location is 16q23.3. The type 2 enzyme was capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. HSD17B2 mRNA was detected in 18 of 42 (43 % ) adenomas but not in prolactinomas. In the human endometrium, inactivation of 17-beta-estradiol to estrone is catalyzed by HSD17B2. And HSD17B2 activity distinguishing between disease-free and diseased endometria. HSD17B2 efficiently catalyzes the oxidative metabolism of androgens and estrogens, and it is expressed in a large series of human peripheral tissues. The previous paradigm that HSD17B2 activity in the endometrium is elevated during the secretory phase is confined to diseased endometrium but not to disease-free endometrium.
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UniProt
- P37059
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途径
- Steroid Hormone Biosynthesis
抗原
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