HAS1 抗体
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北京 101111
Quick Overview for HAS1 抗体 (ABIN7881135)
抗原
See all HAS1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- HAS1 Antibody / Hyaluronan synthase 1
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序列
- NRAEDLYMVD MFREVFADED PATYVWDGNY HQPWEPA
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids NRAEDLYMVDMFREVFADEDPATYVWDGNYHQPWEPA were used as the immunogen for the HAS1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the HAS1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the HAS1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- HAS1 (Hyaluronan Synthase 1 (HAS1))
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别名
- HAS1
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背景
- Hyaluronan synthase 1 is an enzyme that in humans is encoded by the HAS1 gene. This gene is mapped to 19q13.41. Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. AS1 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homology to the hasA gene product of Streptococcus pyogenes, a glycosaminoglycan synthetase (DG42) from Xenopus laevis, and a recently described murine hyaluronan synthase.
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UniProt
- Q92839
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途径
- Glycosaminoglycan Metabolic Process
抗原
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