Recombinant HAUS7 抗体
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北京 101111
Quick Overview for Recombinant HAUS7 抗体 (ABIN7880957)
抗原
See all HAUS7 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- HAUS7 Antibody / UCHL5IP
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human UCHL5IP was used as the immunogen for the HAUS7 antibody.
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亚型
- IgG
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anti-HAUS Augmin-Like Complex, Subunit 7 (HAUS7) antibody
KD Validated HAUS7 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4485 unconjugated Recombinant Antibody
anti-HAUS Augmin-Like Complex, Subunit 7 (HAUS7) (AA 4-319) antibodyHAUS7 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-HAUS Augmin-Like Complex, Subunit 7 (HAUS7) (AA 1-227) antibodyHAUS7 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-HAUS Augmin-Like Complex, Subunit 7 (HAUS7) (AA 1-368) antibodyHAUS7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F2 unconjugated
anti-HAUS Augmin-Like Complex, Subunit 7 (HAUS7) (AA 318-368) antibodyHAUS7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-HAUS Augmin-Like Complex, Subunit 7 (HAUS7) (AA 143-192) antibodyHAUS7 适用: 人, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-HAUS Augmin-Like Complex, Subunit 7 (HAUS7) (AA 4-33), (N-Term) antibodyHAUS7 适用: 人 WB 宿主: 兔 Polyclonal RB30399 unconjugated
anti-HAUS Augmin-Like Complex, Subunit 7 (HAUS7) (Middle Region) antibodyHAUS7 适用: 人, 小鼠, 犬, 马, 兔, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-HAUS Augmin-Like Complex, Subunit 7 (HAUS7) (AA 127-369) antibodyHAUS7 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the HAUS7 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the HAUS7 antibody at -20oC.
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- HAUS7 (HAUS Augmin-Like Complex, Subunit 7 (HAUS7))
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别名
- HAUS7
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背景
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HAUS7 antibody detects HAUS augmin-like complex subunit 7, a protein encoded by the HAUS7 gene that contributes to mitotic spindle organization. HAUS7 is part of the augmin complex, an eight-subunit assembly that recruits gamma tubulin ring complexes to existing microtubules, amplifying spindle microtubule formation during mitosis. This process ensures accurate chromosome alignment and segregation, supporting genomic stability.
HAUS7 antibody is widely used in cell biology and cancer research. The augmin complex promotes branching microtubule nucleation, a mechanism essential for robust spindle assembly in dividing cells. By detecting HAUS7, researchers can study how spindle architecture is generated and maintained. Disruption of augmin components leads to spindle defects, chromosome missegregation, and aneuploidy, processes often linked to tumorigenesis.
Western blot assays detect HAUS7 protein bands in dividing cell extracts. Immunohistochemistry highlights HAUS7 expression in proliferative tissues, while immunofluorescence maps localization at mitotic spindles. These approaches allow detailed analysis of augmin function in cell division.
HAUS7 and other augmin subunits play roles in neural stem cell division, embryonic development, and tissue regeneration. Their contribution to faithful chromosome segregation highlights their importance for preventing genomic instability and disease. By applying HAUS7 antibody, scientists can investigate mechanisms linking spindle regulation to cancer and developmental disorders.
HAUS7 antibody from NSJ Bioreagents provides dependable specificity for studying microtubule nucleation and spindle organization. Its strong performance across methods ensures accurate detection in diverse research contexts. -
UniProt
- Q99871
抗原
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